PLEASE NOTE: These digital lecture materials are the intellectual property of the course instructor, and as such should not be shared with anyone outside of the participating institution.


Lecture Handouts:


Week 1 - December 18-22, 2023

Lecture 01: Course Introduction & Overview

Lecture 02: Radiation Chemistry

Lecture 03: DNA Repair & DNA Damage Response

Lecture 04: Genetic, Cytogenetic & Epigenetic Effects

Lecture 05: Mechanisms of Cell Death  

Lecture 06: Survival & Dose Response Curves

Lecture 07: Sublethal & Potentially Lethal Damage Recovery

Lecture 08: Radiation & The Mammalian Cell Cycle

Lecture 09: LET, RBE & High LET Radiotherapy

Lecture 10: Radiation Carcinogenesis & Risk Assessment


> Sample Boards Questions for Lectures 01-10 (PowerPoint)


Week 2 - March 4-8, 2024

Lecture 11: The Oxygen Effect & Tumor Hypoxia 

Lecture 12: Sensitizers, Protectors & Bioreductive Drugs 

Lecture 13: Tumor Angiogenesis & Metastasis

Lecture 14: Immuno-Oncology  

Lecture 15: Mechanisms of Drug Resistance

Lecture 16: Normal Tissue & Tumor Kinetics

Lecture 17: Early & Late Effects  

Lecture 18: Normal Tissue Tolerance

Lecture 19: The Five (or Six?) Rs of Radiotherapy

Lecture 20: The Linear-Quadratic Isoeffect Model


> Sample Boards Questions for Lectures 11-20 (PowerPoint)



Lecture Videos:


Video 01                    Video 11

Video 02                    Video 12 (from 2023)

Video 03                    Video 13

Video 04                    Video 14

Video 05                    Video 15

Video 06                    Video 16

Video 07                    Video 17 (from 2022)

Video 08                    Video 18

Video 09                    Video 19

Video 10                    Video 20                    


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© Elaine M. Zeman, Ph.D., 2024